527-07-1

  • Product NameSodium gluconate
  • Molecular FormulaC6H11NaO7
  • Molecular Weight218.139
  • Purity99%
  • Appearancewhite or off-white granular powder
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Product Details

Quick Details

  • CasNo: 527-07-1
  • Molecular Formula: C6H11NaO7
  • Appearance: white or off-white granular powder
  • Purity: 99%

Chinese factory supply Sodium gluconate 527-07-1 in stock with high standard

  • Molecular Formula:C6H11NaO7
  • Molecular Weight:218.139
  • Appearance/Colour:white or off-white granular powder 
  • Melting Point:206 °C (dec.)(lit.) 
  • Boiling Point:673.6 °C at 760 mmHg 
  • Flash Point:375.2 °C 
  • PSA:141.28000 
  • Density:1.763 g/cm3 
  • LogP:-4.82780 

Sodium gluconate(Cas 527-07-1) Usage

Concrete Admixture

Sodium gluconate (SG) is used as a retarding admixture in concrete, affecting the setting and hardening behaviors of cement. Even at very small dosages, SG can significantly influence the properties of concrete. In concrete engineering, SG is commonly used as an organic retarding admixture. It exhibits a significant retarding effect, good adaptability with superplasticizer systems, and is cost-effective compared to other additives.

Biostimulant

SG has been identified as a biostimulant that enhances the efficiency of the degradation of B[a]p (benzo[a]pyrene), a polycyclic aromatic hydrocarbon.

Geopolymer Application

Sodium gluconate is utilized in the preparation of geopolymers, particularly in conjunction with sewage sludge ash (SSA), aiming to utilize sewage sludge resources. The addition of SG inhibits the setting time of geopolymers, delaying the initial setting time significantly. This delay is attributed to SG interfering with the dissolution of precursor materials and the growth of hydration gel, affecting the early hardening process. Environmental and economic analyses suggest that delaying the setting of geopolymers through SG inclusion is a favorable option compared to altering alkali activators.

Definition

ChEBI: Sodium gluconate is an organic sodium salt having D-gluconate as the counterion. It has a role as a chelator. It contains a D-gluconate.

Production Methods

Sodium gluconate is manufactured by the fermentation of carbohydrate containing the raw material glucose syrup derived from maize. After a crystallisation step, sodium gluconate is separated from the mother liquor by centrifugation, the crystals are dried and then sieved to guarantee the desired granulation. Based on the production process as well as the raw materials used, sodium gluconate is not synthetic natural.

Therapeutic Function

Electrolyte replenisher

Biochem/physiol Actions

Ingestion of sodium gluconate is known to stimulate the production of intestinal butyrate. It is widely used in food, pharmaceutical paper and textile industry. It acts as a chelating agent. Sodium gluconate serves as a detergent in bottle washing formulation.

Safety Profile

Low toxicity by intravenous route. When heated to decomposition it emits acrid smoke and irritating fumes

Synthesis

The calcium gluconate is added into the reaction kettle. Add sulfuric acid aqueous solution while stirring. After mixing for one hour, let it stand for a while and then get it filtered. The filter residue is CaSO4 and gets it removed. The filtrate is added into the neutralization kettle, and a proper amount of Na2CO3 aqueous solution is added to neutralize it. Finally get sodium gluconate through concentration, filtration and drying.

Purification Methods

Crystallise it from a small volume of H2O (solubility is 59g/100mL at 25o), or dissolve it in H2O and add EtOH since it is sparingly soluble in EtOH. It is insoluble in Et2O. It forms a Cu complex in alkaline solution and a complex with Fe in neutral solution. [cf p 639, Sawyer & Bagger J Am Chem Soc 81 5302 1959, Beilstein 3 I 188.]

Regulations

In Europe, sodium gluconate is listed as a generally permitted food additive (E576) and may be added to all foodstuffs, following the "quantum satis" principle, as long as no special regulation restricts the use.The US Food and Drug Administration (FDA) assigned sodium gluconate the “generally recognised as safe” (GRAS) status and permitted its use in food without limitation other than current good manufacturing practice.Sodium gluconate is exempted from the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) by means of Commission Regulation (EC) No. 987/2008 of 8 October, 2008 (amending Annex IV). As a consequence thereof, there is no need to register sodium gluconate.

InChI:InChI=1/C14H14O3.C6H12O7.Na/c1-8(2)7-11(15)12-13(16)9-5-3-4-6-10(9)14(12)17;7-1-2(8)3(9)4(10)5(11)6(12)13;/h3-6,8,12H,7H2,1-2H3;2-5,7-11H,1H2,(H,12,13);/q;;+1/p-1/t;2-,3-,4+,5-;/m.1./s1

527-07-1 Relevant articles

Expanding the scope of laccase-mediator systems

Koenst, Paul,Kara, Selin,Kochius, Svenja,Holtmann, Dirk,Arends, Isabel W. C. E.,Ludwig, Roland,Hollmann, Frank

, p. 3027 - 3032 (2013)

The laccase-mediator system (LMS) for th...

Aerobic oxidation of glucose over gold nanoparticles deposited on cellulose

Ishida, Tamao,Watanabe, Hiroto,Bebeko, Takao,Akita, Tomoki,Haruta, Masatake

, p. 42 - 46 (2010)

Gold nanoparticles (NPs) with mean diame...

Nonenzymatic and metal-free organocatalysis for in situ regeneration of oxidized cofactors by activation and reduction of molecular oxygen

Zhu, Chenjie,Li, Qing,Pu, Lingling,Tan, Zhuotao,Guo, Kai,Ying, Hanjie,Ouyang, Pingkai

, p. 4989 - 4994 (2016)

The application of synthetic flavinium o...

Efficient Oxidation of Glucose into Sodium Gluconate Catalyzed by Hydroxyapatite Supported Au Catalyst

Liu, Xianxiang,Yang, Yongjun,Su, Shengpei,Yin, Dulin

, p. 383 - 390 (2017)

Abstract: Gold nanoparticles (NPs) with ...

Gold Catalysis and Photoactivation: A Fast and Selective Procedure for the Oxidation of Free Sugars

Omri, Mehdi,Sauvage, Frédéric,Busby, Yan,Becuwe, Matthieu,Pourceau, Gwladys,Wadouachi, Anne

, p. 1635 - 1639 (2018)

A fast and efficient methodology for the...

Crystal and molecular structure of N-(n-octyl)-6-deoxy-D-gluconamide: a novel packing of amphiphilic molecules

Herbst, Roswitha,Steiner, Thomas,Pfannemueller, Beate,Saenger, Wolfram

, p. 29 - 42 (1995)

N-(n-octyl)-6-deoxy-D-gluconamide crysta...

Effect of reduction method on the performance of Pd catalysts supported on activated carbon for the selective oxidation of glucose

Chen, Kangcheng,Pan, Yunxiang,Liu, Changjun

, p. 1598 - 1602 (2010)

The effect of the reduction method on th...

TEMPO-mediated oxidation of maltodextrins and D-glucose: Effect of pH on the selectivity and sequestering ability of the resulting polycarboxylates

Thaburet, Jean-Francois,Merbouh, Nabyl,Ibert, Mathias,Marsais, Francis,Queguiner, Guy

, p. 21 - 29 (2001)

Maltodextrins were oxidized to polyglucu...

C1 Oxidation/C2 Reduction Isomerization of Unprotected Aldoses Induced by Light/Ketone

Masuda, Yusuke,Tsuda, Hiromu,Murakami, Masahiro

supporting information, p. 2755 - 2759 (2020/01/25)

Unprotected aldoses in water undergo an ...

Efficient and Bio-inspired Conversion of Cellulose to Formic Acid Catalyzed by Metalloporphyrins in Alkaline Solution

Liu, Qiang,Zhou, Doudou,Li, Zongxiang,Luo, Weiping,Guo, Cancheng

supporting information, p. 1063 - 1068 (2017/07/24)

A bio-inspired approach for efficient co...

527-07-1 Process route

D-Glucose
2280-44-6

D-Glucose

D-Fructose
57-48-7,18875-34-8

D-Fructose

D-Mannose
3458-28-4

D-Mannose

D-sorbitol
50-70-4

D-sorbitol

sodium D-gluconate
527-07-1

sodium D-gluconate

D-glucaric acid disodium salt

D-glucaric acid disodium salt

D-maltose
69-79-4

D-maltose

Conditions
Conditions Yield
With dihydrogen peroxide; sodium hydroxide; In water; at 50 - 60 ℃; Sealed tube;
D-glucose
50-99-7

D-glucose

sodium formate
141-53-7

sodium formate

sodium acetate
127-09-3

sodium acetate

sodium glycolate
25289-18-3,105938-46-3,2836-32-0

sodium glycolate

sodium D-gluconate
527-07-1

sodium D-gluconate

Conditions
Conditions Yield
With oxygen; sodium hydroxide; at 150 ℃; for 2h; under 15001.5 Torr; Reagent/catalyst; Autoclave;
38.14%
5.67%
7.7%
9.83%

527-07-1 Upstream products

  • 50-99-7
    50-99-7

    D-glucose

  • 2280-44-6
    2280-44-6

    D-Glucose

  • 492-61-5
    492-61-5

    β-D-glucose

  • 488-79-9
    488-79-9

    6-deoxy-D-glucose

527-07-1 Downstream products

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    62-76-0

    sodium oxalate

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    10323-20-3

    D-Arabinose

  • 583-50-6
    583-50-6

    D-erythrose

  • 17430-71-6
    17430-71-6

    penta-O-acetyl-D-gluconic acid

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