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InChI:InChI=1/C18H22O5/c1-20-15-8-7-12(9-14(15)19)5-6-13-10-16(21-2)18(23-4)17(11-13)22-3/h7-11,19H,5-6H2,1-4H3
The invention belongs to the technical f...
Disclosed is a 5-fluorouracil derivative...
The invention relates to a lansamine het...
Cancer cell proliferation in some organs...
2-(3-hydroxy-4-methoxyphenyl)-1-(3',4',5'-trimethoxyphenyl)ethyne
erianin
combrestatin A4
Conditions | Yield |
---|---|
With
quinoline; hydrogen;
In
hexane; toluene;
at 20 ℃;
stereoselective reaction;
|
90% |
2-[3-(tert-butyldimethylsilyloxy)-4-methoxyphenyl]-1-(3,4,5-trimethoxyphenyl)ethyne
erianin
combrestatin A4
Conditions | Yield |
---|---|
2-[3-(tert-butyldimethylsilyloxy)-4-methoxyphenyl]-1-(3,4,5-trimethoxyphenyl)ethyne;
With
quinoline; hydrogen;
In
hexane; toluene;
at 20 ℃;
for 1h;
under 760.051 Torr;
With
tetrabutyl ammonium fluoride; water;
In
ethyl acetate;
at 20 ℃;
for 0.25h;
stereoselective reaction;
|
0.12 g |
Multi-step reaction with 2 steps
1: tetrabutyl ammonium fluoride; water / ethyl acetate / 0.17 h / 20 °C
2: quinoline; hydrogen / hexane; toluene / 20 °C
With
quinoline; tetrabutyl ammonium fluoride; water; hydrogen;
In
hexane; ethyl acetate; toluene;
|
combrestatin A4
combretastatin A-4
C24H36O7SSi
(3,4,5-trimethoxyphenyl)methanol
erianin acetate
3,4,5,4'-tetramethoxyl-α,β-diphenylethane-3'-O-sodium sulphate
C18H23O8P
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