Sesamol is white to off-white crystalline powder, while it's Molecular Formula is C7H6O3. white to off-white crystalline powder Sesamol (Paroxetine Anhydrous EP Impurity B) is a natural component of sesame oil with antioxidant activity. Sesamol has potential protective effects against free radicals as well as some antifungal activity. Sesamol can also be used as an intermediate in the preparation of antidepressants such as Paroxetine (P205750).

What is the CAS number for Sesamol?

The CAS number of Sesamol is 533-31-3.

What is Sesamol (533-31-3) used for?

Sesamol is found in sesame seeds and sesame oil. It is a well-known antioxidant. It has antioxidant, chemoprevention, antimutagenic, and antihepatotoxic activities and can induce the apoptosis of cancer and cardiovascular cells. It can be used in the synthesis of paroxetine.InChI:InChI=1/C7H6O3/c8-5-1-2-6-7(3-5)10-4-9-6/h1-3,8H,4H2

533-31-3

Product NameSesamol
Molecular FormulaC₇H₆O₃
Molecular Weight138.123
Purity99%
Appearancewhite to off-white crystalline powder

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Product Details

Quick Details

CasNo： 533-31-3
Molecular Formula： C₇H₆O₃
Appearance： white to off-white crystalline powder
Purity： 99%

Chemical plants supply high-quality Sesamol 533-31-3 in bulk

Molecular Formula:C7H6O3
Molecular Weight:138.123
Appearance/Colour:white to off-white crystalline powder
Melting Point:62-65 °C(lit.)
Refractive Index:1.4850 (estimate)
Boiling Point:274 °C at 760 mmHg
PKA:10.08±0.20(Predicted)
Flash Point:119.5 °C
PSA：38.69000
Density:1.394 g/cm³
LogP:1.12090

Sesamol(Cas 533-31-3) Usage

Reference	M. A. Ansari, Z. Fatima, S. Hameed, Sesamol: A Natural Phenolic Compound with Promising Anticandidal Potential, Journal of Pathogens, vol. 2014, Article ID 895193 T. Geetha, B. Rohit, K. Pal, Sesamol: an efficient antioxidant with potential therapeutic benefits, Medicinal Chemistry, 2009, vol. 5, pp. 367-371
Synthesis Reference(s)	Tetrahedron Letters, 19, p. 3085, 1978 DOI: 10.1016/S0040-4039(01)94947-0
General Description	Sesamol, a principal phytophenol of sesame oil lignans, is typically used as a dietary compound.(10)

InChI:InChI=1/C7H6O3/c8-5-1-2-6-7(3-5)10-4-9-6/h1-3,8H,4H2

533-31-3 Relevant articles

Design and synthesis of 3,4-methylenedioxy-6-nitrophenoxyacetylhydrazone derivatives obtained from natural safrole: New lead-agents with analgesic and antipyretic properties

Bezerra-Netto, Heleno J.C.,Lacerda, Daniel I.,Miranda, Ana Luisa P.,Alves, Helio M.,Barreiro, Eliezer J.,Fraga, Carlos A.M.

, p. 7924 - 7935 (2006)

In this work, we reported the synthesis ...

Formation of Samin Diastereomers by Acid-Catalyzed Transformation of Sesamolin with Hydrogen Peroxide

Chu, I-Hsuan,Hung, Wei-Ching,Lee, Wei-Ju,Su, Nan-Wei,Tsai, Hsin-Ya

, p. 6430 - 6438 (2020)

The conversion of sesame lignans is of i...

Nickel-catalyzed deallylation of aryl allyl ethers with hydrosilanes

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supporting information, (2021/09/28)

An efficient and mild catalytic deallyla...

Synthesis process 3,4 -methylenedioxy phenol

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Paragraph 0027; 0031; 0033; 0037; 0038; 0042; 0043; ..., (2021/10/30)

The invention relates to the technical f...

AN EFFICIENT PROCESS FOR PREPARATION OF ACYL DERIVATIVES OF ALKYLENEDIOXYBENZENES

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, (2021/08/20)

The present disclosure provides a proces...

Preparation method of sesamol

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Paragraph 0022; 0026; 0032-0035, (2021/11/21)

The invention belongs to the technical f...

533-31-3 Process route

: 94839-07-3
3,4-(methylenedioxy)-benzeneboronic acid

: 533-31-3
Sesamol

Conditions

Conditions	Yield
With 2,5-dimethylfuran; zinc(II) phthalocyanine; oxygen; In tetrahydrofuran; at 25 ℃; for 1.5h; under 760.051 Torr; Irradiation; Sealed tube; Schlenk technique;	92%
With dihydrogen peroxide; In water; at 20 ℃; for 0.0833333h;	92%
With oxygen; triethylamine; In 2-methyltetrahydrofuran; at 20 ℃; for 24h; under 760.051 Torr; Green chemistry;	88%
With rongalite; In ethanol; water; at 20 ℃; for 7h; Irradiation;	71%
With [Rh2(bpy)2(μ-OAc)2(OAc)2]; oxygen; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; for 18h; under 760.051 Torr; Irradiation;	30 mg

: 19202-22-3
O-allyl-sesamol

: 533-31-3
Sesamol

Conditions

Conditions	Yield
O-allyl-sesamol; With bis(1,5-cyclooctadiene)nickel ⁽⁰⁾; 1,1,3,3-Tetramethyldisiloxane; 4,4'-di-tert-butyl-2,2'-bipyridine; In N,N-dimethyl-formamide; at 20 ℃; for 8h; Schlenk technique; Inert atmosphere; Sealed tube; With hydrogenchloride; In water; N,N-dimethyl-formamide; at 50 ℃; for 2h; Reagent/catalyst; Schlenk technique; Inert atmosphere; Sealed tube;	92%