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China cas 124750-99-8 manufacturer wholesale Losartan potassium at affordable price. HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD was established on February 7, 2018 and is located in Xingtai, Hebei, an important industrial town in northern China. In 2018, the company was established to operate e-commerce, hardware and electrical equipment, electronic products, etc. In 2019, the company also suffered huge losses due to the global outbreak of COVID-19, so the company transformed into a combination of export cross-border trade and self operated factory production. Li Hairong, Chairman of the Board of Directors, has 11 years of experience in chemical products, and after more than 10 years of continuous efforts and integration, has gradually formed a good pattern with the School of Chemical Engineering of Shanghai Jiaotong University, the School of Chemical Engineering of East China University of Science and Technology, the School of Chemistry and Chemical Engineering of Shandong University as the technical support, and Xingtai, Hebei Province as the domestic and foreign trade marketing platform. The company has 3 production bases. Respectively in Hebei, Inner Mongolia, Yunnan three factory bases. It has two research centers and three laboratories specializing in the development of new products and the optimization of existing products. We supply high quality Losartan potassium (CAS 124750-99-8), in stock, factory directly supply to clients, lower prices, more competitiveness.
Losartan potassium is white to off-white crystalline powder, while it's Molecular Formula is C22H22ClKN6OK. Coronary vasodilator used in the diagnosis of coronary heart disease (adenosine A2A agonist).
The CAS number of Losartan potassium is 124750-99-8.
More information of Losartan potassium 124750-99-8 are:
Synonyms |
Lotim;L-158086;Ocsaar;Losacor;Tenopres;Lortaan;Losaprex;Hyzaar;Niten;DuP 753;Losartan monopotassium salt;MK 954;Lorzaan;Cozaar;Llosartan;Losartanpotassium;Lorzaar;1H-Imidazole-5-methanol,2-butyl-4-chloro- 1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]- methyl]-,monopotassium salt;2-Butyl-4-chloro-1-(2-(tetrazol-5-yl)biphenyl-4-ylmethyl)-1H-imidazole-5-methanol potassium;MK-0954;Losacar;MK 0954;potassium [2-butyl-5-chloro-3-[[4-[2-(2,3,4-triaza-1-azanidacyclopenta-2,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol;Cozaar (TN); |
CAS Number |
124750-99-8 |
Molecular Formula |
C22H22ClKN6OK |
Molecular Weight |
461.008 |
Density |
0.986g/mLat 25°C(lit.) |
Melting Point |
?69°C(lit.) |
Boiling Point |
682 °C at 760mmHg |
Flash Point |
366.3 °C |
HS CODE |
2933290000 |
PSA |
89.61000 |
LogP |
3.89590 |
Losartan potassium is the first potent and selective non-peptide angiotensin II (AT II) AT1 receptor antagonist introduced to the market as a once-daily oral antihypertensive. It is efficacious and long lasting in controlling blood pressure in spontaneous hypertensive rats, in patients with essential hypertension in addition to those patients with renal impairment. Since losartan functions by competitive antagonism at the level of receptor, which represents the most direct way of selectively inhibiting the renin-angiotensin system (RAS) independent of the source of AT II, its use has been reported to be free of the coughing side effect exhibited by the ACE inhibitors. In contrast to calcium channel blockers, losartan does not appear to cause ankle edema, headache and tachycardia. It is also reported to be in clinical trials for the treatment of heart failure. Other reports indicate that losartan may have potential efficacy as an anxiolytic, an antiglaucoma agent, in addition to in providing protection against stroke and in preventing the myointimal proliferative response of the vascular wall after coronary angioplasty and surgery.
InChI:InChI=1/C22H22ClN6O.K/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22;/h4-7,9-12H,2-3,8,13-14H2,1H3,(H,25,26,27,28);/q-1;+1
Articles related to Losartan potassium:
Article |
Source |
COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING SALT SENSITIVITY OF BLOOD PRESSURE |
- , (2015/02/05) |
An efficient, commercially viable, and safe process for preparation of losartan potassium, an angiotensin II receptor antagonist |
Madasu, Suri Babu,Vekariya,Koteswaramma, Ch,Islam, Aminul,Sanasi, Paul Douglas,Korupolu, Raghu Babu , p. 2025 - 2030 (2013/02/25) |
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD is a quality supplier and manufacturer of Losartan potassium . You can buy high quality, low price Losartan potassium 124750-99-8 here. Contact us.
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