484-12-8

  • Product NameOsthole
  • Molecular FormulaC15H16O3
  • Molecular Weight244.29
  • Purity99%
  • AppearanceFine White Powder
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Product Details

Quick Details

  • CasNo: 484-12-8
  • Molecular Formula: C15H16O3
  • Appearance: Fine White Powder
  • Purity: 99%

Top Quality Chinese Manufacturer supply 484-12-8 Osthole We supply high quality Osthole (CAS 484-12-8), in stock, factory directly supply to clients, lower prices, more competitiveness.

What is the Osthole ?

Osthole is Fine White Powder, while it's Molecular Formula is C15H16O3. Osthole inhibits the PI3K/Akt pathway thus inhibiting insulin-like growth factor-1 (IGF-1)-induced epithelial-to-mesenchymal transition (EMT) in brain cancer. Osthole may be used in the treatment of Glioblastoma multiforme (GBM).

What is the CAS number for Osthole ?

The CAS number of Osthole is 484-12-8.

More information of Osthole 484-12-8 are:

Synonyms

8-(3-Methyl-2-butenyl)herniarin;2H-1-Benzopyran-2-one, 7-methoxy-8-(3-methyl-2-butenyl)-;7-Methoxy-8-isopentenylcoumarin;7-methoxy-8-(3-methylbut-2-enyl)chromen-2-one;Coumarin, 7-methoxy-8- (3-methyl-2-butenyl)-;2H-1-Benzopyran-2-one,7-methoxy-8-(3- methyl-2-butenyl)-;Ostol;Coumarin, 7-methoxy-8-(3-methyl-2-butenyl)-;Cnidium monnieri P.E.- Osthole;Common Cnidium Fruit P. E.;Fructus Cnidii;

CAS Number

484-12-8

Molecular Formula

C15H16O3

Molecular Weight

244.29

Density

1.126 g/cm3

Melting Point

83-84 °C

Boiling Point

396.7 °C at 760 mmHg

Flash Point

167.6 °C

HS CODE

29322090

PSA

39.44000

LogP

3.31030

What is Osthole (484-12-8) used for?

Cnidium is a Chinese medicine which is used widely by traditional medicine doctors. Cnidium has been recorded in almost all of the pharmaceutical monographs , including Shen Nong’s Classic Materia Medica, New Materia Medica, Compendium of Materia Medica, etc. Osthole is a major bioactivity compound of the Cnidium, which has the effect of dampness dispelling, insecticidal antipruritic,and aphrodisiac and is used for the treatment for pruritus and eczema, lumbago,kidney impotence, and infertility . Osthole is derived from Umbelliferae and Rutaceae plants. Osthole is also distributed in Asteraceae and Leguminosae plants. Osthole is present in 14 genera of Umbelliferae plants: danggui (Angelica L.), gudanggui (Archangelica Hoffm.), mianguoqin (Cachrys L.), shechuang (Cnidium Cusson), awei (Ferula L.), duhuo (Heracleum L.), yanfeng (Libanotis Hill), ouqin (Petroselinum Hill), qianhu (Peucedanum L.), huiqin (Pimpinella L.), liangshechuang (Selinum L.). Shuanchiqin (Prangos Lindl), xifengqin (Seseli L.), oufangfeng (Pastinaca L.). Osthole is present in 17 genera of Rutaceae plants: ganju (Citrus L.), huangpi (Clausena Burm. F.), xiangju (Feronia Correa), jupanmu (Flindersia R. Br.), niyunxiang (Haplophyllum A. Juss.), mizhuyu (Melicope J. R. and G. Forst.), xiaoyunmu (Micromelum Bl.), jiulixiang (Murraya Koenig ex L.), zhi (Poncirus Raf.), yinyu (Skimmia Thunb.), Limonia, Myrtopsis, Pentaceras, Phebalium, Pilocarpus, Thamnosma, Ticorea) .

InChI:InChI=1/C15H16O3/c1-10(2)4-7-12-13(17-3)8-5-11-6-9-14(16)18-15(11)12/h4-6,8-9H,7H2,1-3H3

Articles related to Osthole:

Article

Source

Palladium-catalyzed synthesis of 8-allyl or 8-prenylcoumarins by using organotin reagents as multicoupling nucleophiles

Yin, Qiang,Yan, Han,Zhang, Yaqin,Wang, Yige,Zhang, Guojin,He, Yuxiang,Zhang, Weihua

, p. 85 - 88 (2013)

Microwave-Assisted Synthesis of Phenylpropanoids and Coumarins: Total Synthesis of Osthol

Konrádová, Daniela,Kozubíková, Hana,Dole?al, Karel,Pospí?il, Ji?í

supporting information, p. 5204 - 5213 (2017/09/29)

How to get the best price on Osthole?

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