What is the Cytosine?

Cytosine is white solid, while it's Molecular Formula is C4H5N3O. white solid Cytosine has been used: for the preparation of nucleobase solutions as a standard for high-performance liquid chromatography (HPLC)for the estimation of global methylation ratefor nucleoside 5′-triphosphate (NTP) synthesis purification

What is the CAS number for Cytosine?

The CAS number of Cytosine is 71-30-7.

What is Cytosine (71-30-7) used for?

Cytosine is pyrimidine; along with adenine and guanine they account for the fi ve nucleic acid bases. Pyrimidines are heterocyclic single-ringed compounds based on the structure of pyrimidine. Cytosinelike adenine and guanine, form nucleosides and nucleotides in RNA and DNA. When the bases combine with ribose, a ribonucleoside forms; and when it attaches to deoxyribose, a deoxyribosenucleoside is formed. Names of the nucleoside are summarized in Table 29.1.these in turn combine with phosphoryl groups, in a process called phosphorylation, to form their respective nucleotides that form nucleic acids.the nucleotides can be tri, di, and mono phosphate nucleotides similar to the way in which adenine forms ATP, ADP, and AMP.InChI:InChI=1/C4H5N3O/c5-3-1-2-6-4(8)7-3/h1-2H,(H3,5,6,7,8)

What is the Cytosine?

Cytosine is white solid, while it's Molecular Formula is C4H5N3O. white solid Cytosine has been used: for the preparation of nucleobase solutions as a standard for high-performance liquid chromatography (HPLC)for the estimation of global methylation ratefor nucleoside 5′-triphosphate (NTP) synthesis purification

What is the CAS number for Cytosine?

The CAS number of Cytosine is 71-30-7.

What is Cytosine (71-30-7) used for?

Cytosine is pyrimidine; along with adenine and guanine they account for the fi ve nucleic acid bases. Pyrimidines are heterocyclic single-ringed compounds based on the structure of pyrimidine. Cytosinelike adenine and guanine, form nucleosides and nucleotides in RNA and DNA. When the bases combine with ribose, a ribonucleoside forms; and when it attaches to deoxyribose, a deoxyribosenucleoside is formed. Names of the nucleoside are summarized in Table 29.1.these in turn combine with phosphoryl groups, in a process called phosphorylation, to form their respective nucleotides that form nucleic acids.the nucleotides can be tri, di, and mono phosphate nucleotides similar to the way in which adenine forms ATP, ADP, and AMP.InChI:InChI=1/C4H5N3O/c5-3-1-2-6-4(8)7-3/h1-2H,(H3,5,6,7,8)

71-30-7

Product NameCytosine
Molecular FormulaC₄H₅N₃O
Molecular Weight111.103
Purity99%
Appearancewhite solid

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Product Details

Quick Details

CasNo： 71-30-7
Molecular Formula： C₄H₅N₃O
Appearance： white solid
Purity： 99%

Factory Export Top Purity Cytosine 71-30-7 In Stock

Molecular Formula:C4H5N3O
Molecular Weight:111.103
Appearance/Colour:white solid
Vapor Pressure:1.46E-08mmHg at 25°C
Melting Point:>300 °C(lit.)
Refractive Index:1.688
Boiling Point:445.8 °C at 760 mmHg
PKA:4.60, 12.16(at 25℃)
Flash Point:223.4 °C
PSA：71.77000
Density:1.55 g/cm³
LogP:-0.06670

Cytosine(Cas 71-30-7) Usage

History	Cytosine is first isolated by hydrolysis of calf thymus tissue by Albrecht Kossel (1853–1927) and A. Neumann during 1893–1894. Thymine’s structure was published in 1900 and confi rmed over the next several years when it was synthesized by several investigators. In 1903, cytosine was synthesized by Henry Lord Wheeler (1867–1914) and Treat B. Johnson, confirming its structure. Uracil was first isolated in 1900 from yeast nucleic acid found in bovine thymus and herring sperm.the methylation of uracil produces thymine; thymine is also called 5-methyluracil because methylation takes place at the fi fth carbon in uracil to produce thymine.
Biochem/physiol Actions	Cytosine (C) is one of the four main bases found in DNA and RNA, along with adenine, guanine, and thymine (uracil in RNA).
Purification Methods	Cytosine crystallises from H2O as the monohydrate which loses water on heating above 100o. Its solubility in H2O is 0.77%. UV: max 267nm ( 6,100) in H2O pH 8.8 and 275nm ( 10,400) in 0.1N HCl. [Hilbert & Johnson J Am Chem Soc 52 1152 1930, Hilbert et al. J Am Chem Soc 57 552 1935, Beistein 25 III/IV 3654.]
Definition	ChEBI: An aminopyrimidine that is pyrimidin-2-one having the amino group located at position 4.
General Description	Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

InChI:InChI=1/C4H5N3O/c5-3-1-2-6-4(8)7-3/h1-2H,(H3,5,6,7,8)

71-30-7 Relevant articles

The aminomethylation of adenine, cytosine and guanine

Sloan,Siver

, p. 3997 - 4001 (1984)

A facile and effective synthesis of lamivudine 5′-diphosphate

Roy, Béatrice,Lefebvre, Isabelle,Puy, Jean-Yves,Périgaud, Christian

, p. 1250 - 1252 (2011)

We report on the first solution synthesi...

2'-C-cyano-2'-deoxy-1-β-D-arabinofuranosyl-cytosine (CNDAC): A mechanism-based DNA-strand-breaking antitumor nucleoside

Matsuda,Azuma

, p. 461 - 471 (1995)

The antitumor mechanism of action of 2'-...

Nucleosides and Nucleotides. 141. Chemical Stability of a new Antitumor Nucleoside, 2'-C-Cyano-2'-deoxy-1-β-D-arabino-pentofuranosylcytosine in Alkaline Medium: Formation of 2'-C-Cyano-2;-deoxy-1-β-D-ribo-pentofuranosylcytosine and Its Antitumor Activity.

Azuma, Atsushi,Hanaoka, kenji,Kurihara, Atsushi,Kobayashi, Tomowo,Miyauchi, Seiji,et al.

, p. 3391 - 3397 (1995)

We have designed 2'-C-Cyano-2'-deoxy-1-β...

Homochiral crystal generation: Via sequential dehydration and Viedma ripening

Sivakumar, Reajean,Askari, Mohammad S.,Woo, Simon,Madwar, Carolin,Ottenwaelder, Xavier,Bohle, D. Scott,Cuccia, Louis A.

, p. 4277 - 4280 (2016)

1,2-Bis(N-benzoyl-N-methylamino)benzene ...

Evidence for C-1' hydrogen abstraction from modified oligonucleotides by Fe-bleomycin

Duff,De Vroom,Geluk,Hecht,Van Der Marel,Van Boom

, p. 3350 - 3351 (1993)

-

Kutscher

, p. 170 (1903)

TET-Like Oxidation in 5-Methylcytosine and Derivatives: A Computational and Experimental Study

Jonasson, Niko S. W.,Jan?en, Rachel,Menke, Annika,Zott, Fabian L.,Zipse, Hendrik,Daumann, Lena J.

, p. 3333 - 3340 (2021/09/25)

The epigenetic marker 5-methylcytosine (...

Monitoring the reactivity of formamide on amorphous SiO2 by in-situ UV-Raman spectroscopy and DFT modeling

Balucani, Nadia,Bonino, Francesca,Martra, Gianmario,Pantaleone, Stefano,Signorile, Matteo,Ugliengo, Piero

, (2020/05/28)

Formamide has been recognized in the lit...

Sources of 2,5-diaminoimidazolone lesions in DNA damage initiated by hydroxyl radical attack

Thomas, Caroline Suzanne,Pollard, Hannah Catherine,Razskazovskiy, Yuriy,Roginskaya, Marina

, p. 517 - 524 (2020/09/07)

The present study reports radiation-chem...

Dehalogenation of Halogenated Nucleobases and Nucleosides by Organoselenium Compounds

Mondal, Santanu,Mugesh, Govindasamy

, p. 1773 - 1780 (2019/01/10)

Halogenated nucleosides, such as 5-iodo-...

71-30-7 Process route

: 123413-57-0
N⁴-benzoyl-2',3'-didehydro-2',3'-dideoxycytidine

: 26661-13-2
4-N-benzoylcytosine

: 71-30-7
Cytosine

Conditions

Conditions	Yield
In water; at 40 ℃; Rate constant; degradation in various buffers (acidic condition, < pH 6);

: 77287-34-4,77287-35-5,60100-09-6
formamide

: 51953-18-5,542-27-8
pyrimidine-4(3H)-one

: 156-81-0
2,4-diaminopyrimidine

: 120-89-8
parabanic acid

: 108-53-2,145358-63-0,674-97-5,176772-97-7
isocytosine

: 71-30-7
Cytosine

: 144-62-7,97993-78-7
oxalic acid

: 113-00-8
guanidine nitrate

: 127-17-3
2-oxo-propionic acid

: 66-22-8,144104-68-7,18324-22-6,27072-01-1,2920-92-5,51953-19-6
uracil

: 56-06-4
2,6-diaminopyrimidin-4-ol

: 66224-66-6,66224-67-7,66224-68-8,66224-69-9,134434-48-3,134434-49-4,134454-76-5,134461-75-9
adenine

: 57-13-6
urea

: 56-40-6,18875-39-3,25718-94-9
glycine