497-76-7

  • Product NameArbutin
  • Molecular FormulaC12H16O7
  • Molecular Weight272.255
  • Purity99%
  • AppearanceWhite needle crystal or powder
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  • CasNo: 497-76-7
  • Molecular Formula: C12H16O7
  • Appearance: White needle crystal or powder
  • Purity: 99%

High Quality Chinese Factory supply 497-76-7 Arbutin We provide high quality Arbutin (CAS 497-76-7), at a very affordable prices to our customers.

1.What is the Arbutin ?

Arbutin is a glycosylated hydroquinone that has been found in Arctostaphylos plants and has diverse biological activities, including tyrosinase inhibitory, antioxidant, and anti-inflammatory properties. It inhibits human tyrosinase activity in crude tyrosinase solution isolated from human melanocytes (IC50s = 5.7 and 18.9 mM using L-tyrosine and L-DOPA as substrates, respectively) as well as in intact melanocytes (IC50 = 0.5 mM). Arbutin (50 μM) inhibits hemolysis induced by the free radical generator AAPH in sheep erythrocytes and inhibits AAPH-induced decreases in cell viability in cultured human skin fibroblasts when used at concentrations greater than 125 μM. In an LPS-induced rat model of acute lung injury, arbutin (50 mg/kg) prevents increases in IL-1β, IL-6, and TNF-α levels in lung tissue and serum. Formulations containing arbutin have been used in the treatment of hyperpigmentation disorders.

Arbutin has bactericidal, anti-inflammatory, and whitening effects and is mainly used in whitening cosmetics.

veterinary drug

2.What is the CAS number for Arbutin ?

The CAS number of Arbutin is 497-76-7.

More information of Arbutin 497-76-7 are:

CAS Number

497-76-7

Density

1.556 g/cm3

Melting Point

195-198 °C

Boiling Point

561.583 °C at 760 mmHg

Flash Point

293.435 °C

Vapor Pressure

1.9E-13mmHg at 25°C

Refractive Index

-65.5 ° (C=4, H2O)

HS CODE

2938.90 CLASSIFICATION

PSA

119.61000

LogP

-1.42910

Pka

10.10±0.15(Predicted)

3.What is the molecular formula of Arbutin ?

The chemical formula of Arbutin is C12H16O7 which containing 12 Carbon atoms,16 Hydrogen atoms and 7 Oxygen atoms,and the molecular weight, and the molecular weight of Arbutin is 272.255

4.What is Arbutin(497-76-7)used for?

Arbutin is a glycosylated hydroquinone that has been found in Arctostaphylos plants and has diverse biological activities, including tyrosinase inhibitory, antioxidant, and anti-inflammatory properties. It inhibits human tyrosinase activity in crude tyrosinase solution isolated from human melanocytes (IC50s = 5.7 and 18.9 mM using L-tyrosine and L-DOPA as substrates, respectively) as well as in intact melanocytes (IC50 = 0.5 mM). Arbutin (50 μM) inhibits hemolysis induced by the free radical generator AAPH in sheep erythrocytes and inhibits AAPH-induced decreases in cell viability in cultured human skin fibroblasts when used at concentrations greater than 125 μM. In an LPS-induced rat model of acute lung injury, arbutin (50 mg/kg) prevents increases in IL-1β, IL-6, and TNF-α levels in lung tissue and serum. Formulations containing arbutin have been used in the treatment of hyperpigmentation disorders.

InChI:InChI=1/C12H16O7/c13-5-8-9(15)10(16)11(17)12(19-8)18-7-3-1-6(14)2-4-7/h1-4,8-17H,5H2/t8-,9+,10+,11-,12-/m1/s1

Relevant articles related to Arbutin:

Article

Source

Multienzymic synthesis of poly(hydroquinone) for use as a redox polymer

Wang, Ping,Martin, Brett D.,Parida, Sanghamitra,Rethwisch, David G.,Dordick, Jonathan S.

, p. 12885 - 12886 (1995)

Preparation method of glucoside and derivatives thereof

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Paragraph 0030-0031; 0034; 0035; 0039, (2020/04/02)

5.High Quality Chinese Factory supply 497-76-7 Arbutin

HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD is a quality supplier of Arbutin. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on Arbutin 497-76-7.

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