Your Location:Home >Products >Cosmetic raw material >497-76-7
Product Details
High Quality Chinese Factory supply 497-76-7 Arbutin We provide high quality Arbutin (CAS 497-76-7), at a very affordable prices to our customers.
Arbutin is a glycosylated hydroquinone that has been found in Arctostaphylos plants and has diverse biological activities, including tyrosinase inhibitory, antioxidant, and anti-inflammatory properties. It inhibits human tyrosinase activity in crude tyrosinase solution isolated from human melanocytes (IC50s = 5.7 and 18.9 mM using L-tyrosine and L-DOPA as substrates, respectively) as well as in intact melanocytes (IC50 = 0.5 mM). Arbutin (50 μM) inhibits hemolysis induced by the free radical generator AAPH in sheep erythrocytes and inhibits AAPH-induced decreases in cell viability in cultured human skin fibroblasts when used at concentrations greater than 125 μM. In an LPS-induced rat model of acute lung injury, arbutin (50 mg/kg) prevents increases in IL-1β, IL-6, and TNF-α levels in lung tissue and serum. Formulations containing arbutin have been used in the treatment of hyperpigmentation disorders.
Arbutin has bactericidal, anti-inflammatory, and whitening effects and is mainly used in whitening cosmetics.
veterinary drug
The CAS number of Arbutin is 497-76-7.
More information of Arbutin 497-76-7 are:
CAS Number |
497-76-7 |
Density |
1.556 g/cm3 |
Melting Point |
195-198 °C |
Boiling Point |
561.583 °C at 760 mmHg |
Flash Point |
293.435 °C |
Vapor Pressure |
1.9E-13mmHg at 25°C |
Refractive Index |
-65.5 ° (C=4, H2O) |
HS CODE |
2938.90 CLASSIFICATION |
PSA |
119.61000 |
LogP |
-1.42910 |
Pka |
10.10±0.15(Predicted) |
The chemical formula of Arbutin is C12H16O7 which containing 12 Carbon atoms,16 Hydrogen atoms and 7 Oxygen atoms,and the molecular weight, and the molecular weight of Arbutin is 272.255
Arbutin is a glycosylated hydroquinone that has been found in Arctostaphylos plants and has diverse biological activities, including tyrosinase inhibitory, antioxidant, and anti-inflammatory properties. It inhibits human tyrosinase activity in crude tyrosinase solution isolated from human melanocytes (IC50s = 5.7 and 18.9 mM using L-tyrosine and L-DOPA as substrates, respectively) as well as in intact melanocytes (IC50 = 0.5 mM). Arbutin (50 μM) inhibits hemolysis induced by the free radical generator AAPH in sheep erythrocytes and inhibits AAPH-induced decreases in cell viability in cultured human skin fibroblasts when used at concentrations greater than 125 μM. In an LPS-induced rat model of acute lung injury, arbutin (50 mg/kg) prevents increases in IL-1β, IL-6, and TNF-α levels in lung tissue and serum. Formulations containing arbutin have been used in the treatment of hyperpigmentation disorders.
InChI:InChI=1/C12H16O7/c13-5-8-9(15)10(16)11(17)12(19-8)18-7-3-1-6(14)2-4-7/h1-4,8-17H,5H2/t8-,9+,10+,11-,12-/m1/s1
Relevant articles related to Arbutin:
Article |
Source |
Multienzymic synthesis of poly(hydroquinone) for use as a redox polymer |
Wang, Ping,Martin, Brett D.,Parida, Sanghamitra,Rethwisch, David G.,Dordick, Jonathan S. , p. 12885 - 12886 (1995) |
Preparation method of glucoside and derivatives thereof |
- Paragraph 0030-0031; 0034; 0035; 0039, (2020/04/02) |
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD is a quality supplier of Arbutin. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on Arbutin 497-76-7.
CAS:3081-61-6
CAS:85070-48-0
CAS:1310-73-2
CAS:36653-82-4