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Povidone iodine is a complex of iodine with povidone. It occurs as a yellowish brown to reddish brown amorphous powder, having a slight characteristic odour. Its solution is acid to litmus. Soluble in water and in alcohol, practically insoluble in chloroform, in carbon tetrachloride, in ether, in solvent hexane, and in acetone. It is an external antiseptic with a broad microbicidal spectrum against bacteria, fungi, viruses, protozoa, and yeasts. This gel has about 1.0% available iodine.
Povidone iodine is iodophor, used as topical antiseptic in surgery and for skin and mucous membrane infections, also as aerosol. A 10% povidone iodine solution contains 1% available iodine, but free-iodine is at 0.1% concentration. Skin exposure causes irritant rather than allergic contact dermatitis. In such a situation, however, iodine seems to be the true hapten.
The CAS number of Povidone iodine is 25655-41-8.
Synonyms for Povidone iodine 25655-41-8:Polyvinylpyrrolidone - iodine complex;Tegodyne;Poly(1-(2-Oxo-1-Pyrrolidinyl)Ethylene)-Iodine Complex;Povidoneiodine;1-Ethenyl-2-pyrrolidinone homopolymer compound with iodine;1-Vinyl-2-pyrrolidinone polymer, compd. with iodine;2-Pyrrolidinone, 1-ethenyl-, homopolymer, compd. with iodine;Argentyne;Povidone Iodine Solution;Povidone-iodine;
Polyvinylpyrrolidone-iodine complex is used as a slow iodine release formulation that iodinates lipids and oxidizes cell compounds such as tyrosine side chains. It is utilized to study microbial decontamination of human donor eyes as well as inactivation of infectious hematopoietic necrosis virus. It is also used as a carbon nanotube coating agent to enhance water solubility. It serves as a topical antiseptic in surgery, as an aerosol for skin and mucous membrane infections and is used to prevent infection in wounds.
The major indications of Povidone iodine are as follows: 1. it can be used for treating suppurative dermatitis, fungal skin infection, and small area of ??mild burns; can also be used for disinfection of small area of ??skin and mucous membrane wound. 2.It can be used for the prevention and tropic disinfection of various kinds of diseases such as bacterial and mould vaginitis, cervical erosion, trichomonas vaginitis, genital itching, smelly genital infection, yellow and smelly leucorrhea, comprehensive genital inflammation, elderly vaginitis, herpes, gonorrhea, syphilis and genital warts. 3. It can be used for treating glans inflammation, posthitis, and the disinfection of genitalia and the surrounding area. Also used for the prevention and tropical treatment and disinfection of gonorrhea, syphilis, and genital warts. 4.it can be applied to the disinfection of cutlery and tableware. 5. it can be used or the disinfection surgical area of skin.
InChI:InChI=1/C6H9NO.I2/c1-2-7-5-3-4-6(7)8;1-2/h2H,1,3-5H2;
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