What is the 3-Hydroxy-4-methoxycinnamic acid?

3-Hydroxy-4-methoxycinnamic acid is Off-white crystalline solid, while it's Molecular Formula is C10H10O4. Off-white crystalline solid 3-Hydroxy-4-methoxycinnamic acid was used in the synthesis of tranilast and various tranilast analogs (cinnamoyl anthranilates) by genetically engineered Saccharomyces cerevisiae yeast strain. It was also used in the synthesis of glycoside compounds by undergoing glycosidation.

What is the CAS number for 3-Hydroxy-4-methoxycinnamic acid?

The CAS number of 3-Hydroxy-4-methoxycinnamic acid is 537-73-5.

What is 3-Hydroxy-4-methoxycinnamic acid (537-73-5) used for?

3-Hydroxy-4-methoxycinnamic acid, also known as Isoferulic acid, is a bioactive metabolite predominantly found in its trans form as white crystals. It is isolated from the aerial part of the Chinese medicinal plant Artemisia capillaris and is a component of Chinese herbal medicine with various applications, including as a painkiller and stomachic. 3-Hydroxy-4-methoxycinnamic acid is also an efficient acetylcholine inhibitor and increases the resistance of low-density lipoprotein (LDL) to oxidation.InChI:InChI=1/C10H10O4/c1-14-9-4-2-7(6-8(9)11)3-5-10(12)13/h2-6,11H,1H3,(H,12,13)/p-1/b5-3+

What is the 3-Hydroxy-4-methoxycinnamic acid?

3-Hydroxy-4-methoxycinnamic acid is Off-white crystalline solid, while it's Molecular Formula is C10H10O4. Off-white crystalline solid 3-Hydroxy-4-methoxycinnamic acid was used in the synthesis of tranilast and various tranilast analogs (cinnamoyl anthranilates) by genetically engineered Saccharomyces cerevisiae yeast strain. It was also used in the synthesis of glycoside compounds by undergoing glycosidation.

What is the CAS number for 3-Hydroxy-4-methoxycinnamic acid?

The CAS number of 3-Hydroxy-4-methoxycinnamic acid is 537-73-5.

What is 3-Hydroxy-4-methoxycinnamic acid (537-73-5) used for?

3-Hydroxy-4-methoxycinnamic acid, also known as Isoferulic acid, is a bioactive metabolite predominantly found in its trans form as white crystals. It is isolated from the aerial part of the Chinese medicinal plant Artemisia capillaris and is a component of Chinese herbal medicine with various applications, including as a painkiller and stomachic. 3-Hydroxy-4-methoxycinnamic acid is also an efficient acetylcholine inhibitor and increases the resistance of low-density lipoprotein (LDL) to oxidation.InChI:InChI=1/C10H10O4/c1-14-9-4-2-7(6-8(9)11)3-5-10(12)13/h2-6,11H,1H3,(H,12,13)/p-1/b5-3+

537-73-5

Product Name3-Hydroxy-4-methoxycinnamic acid
Molecular FormulaC₁₀H₁₀O₄
Molecular Weight194.187
Purity99%
AppearanceOff-white crystalline solid

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Product Details

Quick Details

CasNo： 537-73-5
Molecular Formula： C₁₀H₁₀O₄
Appearance： Off-white crystalline solid
Purity： 99%

High Quality Chinese Manufacturer supply 537-73-5 3-Hydroxy-4-methoxycinnamic acid

Molecular Formula:C10H10O4
Molecular Weight:194.187
Appearance/Colour:Off-white crystalline solid
Vapor Pressure:1.83E-07mmHg at 25°C
Melting Point:230 °C (dec.)(lit.)
Refractive Index:1.5168 (estimate)
Boiling Point:410.2 °C at 760 mmHg
PKA:4.53±0.10(Predicted)
Flash Point:167.6 °C
PSA：66.76000
Density:1.316 g/cm³
LogP:1.49860

3-Hydroxy-4-methoxycinnamic acid(Cas 537-73-5) Usage

Definition

ChEBI: A ferulic acid consisting of trans-cinnamic acid bearing methoxy and hydroxy substituents at positions 4 and 3 respectively on the phenyl ring.

General Description

3-Hydroxy-4-methoxycinnamic acid, predominantly trans is available as white crystals. 3-Hydroxy-4-methoxycinnamic acid is isolated from the aerial part of Artemisia capillaris, Chinese medicinal plant. It is a component of chinese herbal medicine used for a pain killer and stomachic. It is an efficient acetylcholine inhibitor. 3-Hydroxy-4-methoxycinnamic acid is bioactive metabolite of Spilanthes acmella Murr. It increases the resistance of low-density lipoprotein (LDL) to oxidation.

InChI:InChI=1/C10H10O4/c1-14-9-4-2-7(6-8(9)11)3-5-10(12)13/h2-6,11H,1H3,(H,12,13)/p-1/b5-3+

537-73-5 Relevant articles

New long-chained feruloyl ester from the bark of Cedrelinga catenaeformis

El-Seedi

, p. 256 - 258 (2007)

Tetradecyl ferulate and a new n-alkyl es...

Isoferuloyl derivatives of five seed glucosinolates in the crucifer genus Barbarea

Agerbirk, Niels,Olsen, Carl Erik

, p. 610 - 623 (2011)

Five acylated glucosinolates (GSLs) were...

ERYTHRINASINATE, AN ESTER FROM THREE ERYTHRINA SPECIES

Fomum, Z. Tanee,Ayafor, J. Foyere,Wandji, Jean,Fomban, W. Gana,Nkengfack, A. Ephrem

, p. 757 - 759 (1986)

The novel ester n-octacosanyl-3-hydroxy-...

Regioselectivity of Cobalamin-Dependent Methyltransferase Can Be Tuned by Reaction Conditions and Substrate

Pompei, Simona,Grimm, Christopher,Farnberger, Judith E.,Schober, Lukas,Kroutil, Wolfgang

, p. 5977 - 5983 (2020/10/06)

Regioselective reactions represent a sig...

Structural features and antioxidant activities of Chinese quince (Chaenomeles sinensis) fruits lignin during auto-catalyzed ethanol organosolv pretreatment

Cheng, Xi-Chuang,Guo, Xin-Ran,Liu, Hua-Min,Liu, Yu-Lan,Qin, Zhao,Wang, Xue-De

, p. 4348 - 4358 (2020/09/22)

Chinese quince fruits (Chaenomeles sinen...

Bioassay of ferulic acid derivatives as influenza neuraminidase inhibitors

Cui, Man-Ying,Xiao, Meng-Wu,Xu, Lv-Jie,Chen, Yun,Liu, Ai-Lin,Ye, Jiao,Hu, Ai-Xi

, (2019/11/13)

Four series of ferulic acid derivatives ...

Copper and L-(?)-quebrachitol catalyzed hydroxylation and amination of aryl halides under air

Bao, Xuefei,Chen, Guoliang,Dong, Jinhua,Du, Fangyu,Li, Hui,Liang, Xinjie,Wu, Ying,Zhang, Yongsheng

supporting information, (2020/08/03)

L-(?)-Quebrachitol, a natural product ob...

537-73-5 Process route

: 621-59-0
isovanillin

: 141-82-2
malonic acid

: 537-73-5
trans-3-hydroxy-4-methoxycinnamic acid

Conditions

Conditions	Yield
With piperidine; pyridine; for 3h; Heating;	94%
With piperidine; pyridine; In ethanol; for 3h; Heating;	92%
With pyridine; acetic acid; at 130 ℃; for 0.333333h; microwave irradiation;	86%
With N,N-dimethyl acetamide; triethylamine; N,N-dimethyl-formamide; In toluene; for 4h; Reflux;	85%
With piperidine; pyridine; In toluene; at 110 ℃; for 12h; Dean-Stark;	78.4%
With pyridine; 1,8-diazabicyclo[5.4.0]undec-7-ene; for 4h; Reflux; Inert atmosphere;	77.2%
With piperidine; pyridine; at 120 ℃; for 4h;	58%
With piperidine; pyridine; for 3.5h; Heating;	52%
With piperidine; pyridine;
With piperidine; In pyridine;
In pyridine; for 3h; Heating;
With piperidine; pyridine; at 90 ℃;
isovanillin; malonic acid; With piperidine; pyridine; at 120 ℃; for 6h; With hydrogenchloride; In water; pH=3;
With piperidine; In pyridine; at 120 ℃; for 1.5h;
With pyridine; at 90 ℃;
With pyridine; aniline; In toluene; at 95 ℃;