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Product Details
Biochem/physiol Actions |
Mangiferin has various pharmacological properties including antioxidant, anti-diabetic, anti-bacterial, cardioprotective, neuroprotective, and immunomodulatory activities. It has also displayed antidiabetic, antihyperlipidemic, and antiatherogenic properties in streptozotocin-induced diabetic rats. MGF exerts chemotherapeutic and chemo-preventative activities. It displays antioxidant, analgesic, and hepatoprotective activity against carbon tetrachloride-induced liver injury. MGF is a known accelerator of gastrointestinal transit (GIT). |
Definition |
ChEBI: A C-glycosyl compound consisting of 1,3,6,7-tetrahydroxyxanthen-9-one having a beta-D-glucosyl residue at the 6-position. |
General Description |
Mangiferin (MGF) is a natural bioactive polyphenol predominantly isolated from the Mangifera indica (Mango) tree. It has a xanthone glucoside structure. Mangiferin can also be found in other angiosperm plants and herbs. |
InChI:InChI=1/C19H18O11/c20-4-11-15(25)17(27)18(28)19(30-11)12-8(23)3-10-13(16(12)26)14(24)5-1-6(21)7(22)2-9(5)29-10/h1-3,11,15,17-23,25-28H,4H2/t11-,15-,17+,18-,19?/m1/s1
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The electrochemical behavior of mangifer...
Total synthesis of mangiferin, homomangi...
The catalytic promiscuity of the novel b...
Mangiferin, isomangiferin, and homomangi...
1,6,7-trihydroxy-2-C-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-3-O-benzylxanthone
mangiferin
Conditions | Yield |
---|---|
With 10% palladium hydroxide on charcoal; hydrogen; In methanol; at 20 ℃; for 48h; under 760.051 Torr;
|
90% |
2-C-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-6-methoxy-1,3,7-trihydroxyxanthone
mangiferin
Conditions | Yield |
---|---|
With boron tribromide; In dichloromethane; at 0 - 20 ℃;
|
94% |
3-glucosyl-2,3′,4,4′,6-pentahydroxybenzophenone
mangiferin-6’-O-gallate
maclurin 3-C-(6''-O-p-hydroxybenzoyl)-β-D-glucoside
maclurin 3-C-(2''-O-p-hydroxybenzoyl-6''-O-galloyl)-β-D-glucoside
norathyriol
1,6,7-trihydroxy-3-methoxylxanthone-2-C-β-D-glucopyranoside
1,3,6-tri-O-benzyl-2-C-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-7-hydroxyxantone
1,3,6-tri-O-benzyl-2-C-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-7-O-acetylxanthone
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