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4773-96-0

  • Product NameMangiferin
  • Molecular FormulaC19H18O11
  • Molecular Weight422.345
  • Purity99%
  • AppearanceLight yellow powder
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Product Details

Quick Details

  • CasNo： 4773-96-0
  • Molecular Formula： C19H18O11
  • Appearance： Light yellow powder
  • Purity： 99%

High Quality Chinese Manufacturer supply 4773-96-0 Mangiferin

  • Molecular Formula:C19H18O11
  • Molecular Weight:422.345
  • Appearance/Colour:Light yellow powder 
  • Vapor Pressure:3.67E-30mmHg at 25°C 
  • Melting Point:269-270°C 
  • Refractive Index:1.788 
  • Boiling Point:842.7 °C at 760 mmHg 
  • PKA:6.09±0.20(Predicted) 
  • Flash Point:303.6 °C 
  • PSA：201.28000 
  • Density:1.843 g/cm3 
  • LogP:-0.71650 

Mangiferin(Cas 4773-96-0) Usage

Biochem/physiol Actions

Mangiferin has various pharmacological properties including antioxidant, anti-diabetic, anti-bacterial, cardioprotective, neuroprotective, and immunomodulatory activities. It has also displayed antidiabetic, antihyperlipidemic, and antiatherogenic properties in streptozotocin-induced diabetic rats. MGF exerts chemotherapeutic and chemo-preventative activities. It displays antioxidant, analgesic, and hepatoprotective activity against carbon tetrachloride-induced liver injury. MGF is a known accelerator of gastrointestinal transit (GIT).

Definition

ChEBI: A C-glycosyl compound consisting of 1,3,6,7-tetrahydroxyxanthen-9-one having a beta-D-glucosyl residue at the 6-position.

General Description

Mangiferin (MGF) is a natural bioactive polyphenol predominantly isolated from the Mangifera indica (Mango) tree. It has a xanthone glucoside structure. Mangiferin can also be found in other angiosperm plants and herbs.

InChI:InChI=1/C19H18O11/c20-4-11-15(25)17(27)18(28)19(30-11)12-8(23)3-10-13(16(12)26)14(24)5-1-6(21)7(22)2-9(5)29-10/h1-3,11,15,17-23,25-28H,4H2/t11-,15-,17+,18-,19?/m1/s1

4773-96-0 Relevant articles

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Markham,K.,Wallace,J.

, p. 415 (1980)

-

Electrochemical investigations into host-guest interactions of a natural antioxidant compound with β-cyclodextrin

Ferreira, Fabricia Da Rocha,Da Silva, Emanuella Gomes,De Leo, Lucila P. Méndez,Calvo, Ernesto J.,Bento, Edson De Souza,Goulart, Marília Oliveira Fonseca,De Abreu, Fabiane Caxico

, p. 797 - 803 (2010)

The electrochemical behavior of mangifer...

Total synthesis of mangiferin, homomangiferin, and neomangiferin

Wei, Xiong,Liang, Danlin,Wang, Qing,Meng, Xiangbao,Li, Zhongjun

, p. 8821 - 8831 (2016/10/03)

Total synthesis of mangiferin, homomangi...

Probing the catalytic promiscuity of a regio- and stereospecific C-glycosyltransferase from Mangifera indica

Chen, Dawei,Chen, Ridao,Wang, Ruishan,Li, Jianhua,Xie, Kebo,Bian, Chuancai,Sun, Lili,Zhang, Xiaolin,Liu, Jimei,Yang, Lin,Ye, Fei,Yu, Xiaoming,Dai, Jungui

supporting information, p. 12678 - 12682 (2015/10/28)

The catalytic promiscuity of the novel b...

Synthesis of mangiferin, isomangiferin, and homomangiferin

Wu, Zhongtao,Wei, Guo,Lian, Gaoyan,Yu, Biao

supporting information; experimental part, p. 5725 - 5728 (2010/10/03)

Mangiferin, isomangiferin, and homomangi...

4773-96-0 Process route

1,6,7-trihydroxy-2-C-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-3-O-benzylxanthone

1,6,7-trihydroxy-2-C-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-3-O-benzylxanthone

mangiferin
4773-96-0

mangiferin

Conditions
Conditions Yield
With 10% palladium hydroxide on charcoal; hydrogen; In methanol; at 20 ℃; for 48h; under 760.051 Torr;
90%
2-C-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-6-methoxy-1,3,7-trihydroxyxanthone
1239694-50-8

2-C-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-6-methoxy-1,3,7-trihydroxyxanthone

mangiferin
4773-96-0

mangiferin

Conditions
Conditions Yield
With boron tribromide; In dichloromethane; at 0 - 20 ℃;
94%

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    1,3,6-tri-O-benzyl-2-C-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-7-O-acetylxanthone

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